The hosts cruised into a comfortable half time lead as Paul Pogba and Anthony Martial converted their penalties, before Pogba notched his second goal of the night with a beautiful curling strike.
Jesse Lingard added a fourth for the hosts in the second half before returning hero Robin van Persie got on the score sheet.
The result means the Reds move into first place ahead of their reverse fixture with Fenerbache in two weeks.
The Red Devils only had one shot on target at Anfield on Monday during their bore 0-0 draw, but Jose Mourinho’s side enjoyed far greater success in front of goal tonight.
But just how did Mourinho's men perform at Old Trafford?
Source :talksport